Nitric oxide disperses the biofilm that grows in catheters, inhibits activation of platelets that clog catheters, and kills the underlying bacteria that causes bloodstream infections.
Nitric oxide is an immune cell signaling molecule that promotes the growth and activity of immune cells.
Nitric oxide covalently binds to DNA, proteins and lipids, thereby inhibiting or killing target pathogens.
Biofilm is a slimy thin film that clings to surfaces, notably human tissue, creating a substrate in which bacteria can grow. Over time, it can grow inside infusion catheters and increase bloodstream infection risk to patients.
Nitric oxide is a proven biofilm disperser, effectively breaking down the film and eradicating the underlying bacteria.
Platelet Aggregation Inhibitor
When blood clots, platelets in the blood are activated to create thrombosis. Clots affect patients using infusion catheters for two reasons. (1) Clots create blockages in catheters that can require expensive intervention by physicians to remedy and put patients at unnecessary risk. (2) Clots act as a substrate on which bacteria can grow, increasing risk of bloodstream infection to patients.
Nitric oxide is a proven platelet aggregation inhibitor, acting as an anticoagulant and effectively keeping blood flowing smoothly.
Safe & Endogenous
Our bodies naturally generate and regulate nitric oxide production for a number of functions.
Nitric oxide has a well-characterized safety profile. Inhaled nitric oxide is FDA approved to treat neonates with pulmonary hypertension .